產品詳情
Cat#:189P03
序列(三字母):H-Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-
Pro-Leu-Glu-Pro-Arg-Arg-Glu-Val-Cys-Glu-Leu-Asn-Pro-Asp-
Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg
-Arg-Phe-Tyr-Gly-Pro-Val-OH trifluoroacetate salt
(Disulfide bond)
序列(單字母):YLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAY
RRFYGPV
類似名:Osteocalcin (1-49) (human) (decarboxylated)
分子式:C???H???N??O??S?
分子量:5797.49
CAS#:1927927-11-4
合成方法:Synthetic
存儲條件:-20 ± 5 °C
應用:Diabetes|
Obesity Research
描述:The peptide hormone osteocalcin is involved not only in
bone formation, it also plays an important role in glucose
metabolism and could regulate testosteron. In mice, only
the completely decarboxylated form of the peptide
shows the latter hormonal activities, whereas in humans,
osteocalcin, partially decarboxylated osteocalcins, and
the uncarboxylated peptide seem to be involved.
Generally, obese individuals have been shown to have
lower osteocalcin(s) levels than non-obese controls,
and type 2 diabetic individuals have lower plasma
osteocalcin than non-diabetic individuals.
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