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Cat#：177P30
序列（三字母）：H-Asn-Pro-Met-Tyr-Asn-Ala-Val-Ser-Asn-Ala-Asp-Leu-Met-Asp-Phe-Lys-Asn-Leu-Leu-Asp-His-Leu-Glu-Glu-Lys-Met-Pro-Leu-Glu-Asp-OH
序列（單字母）：NPMYNAVSNADLMDFKNLLDHLEEKMPLED
類似名：Prepro-hANF (26-55) Cardiodilatin-Related Peptide (human), NT-pro-ANP (human) (1-30), Prepro-ANF (26-55), human
分子式：C???H???N??O??S?
分子量：3507.97
CAS#：112160-82-4
合成方法：Synthetic
存儲(chǔ)條件：-20 ± 5 °C
應(yīng)用：Cardiovascular System & Diseases
描述：Prepro-atrial natriuretic factor (26-55) (human) (NT-pro-ANP (1-30)) is one of four peptide hormones derived from the atrial natriuretic prohormone. It is also known as long acting natriuretic peptide. The peptide has potent vasodilatory properties equal to atrial natriuretic factor. Vasodilation is associated with a 4-5 fold increase in cyclic GMP levels due to activation of particulate guanylate cyclase activity. Like prepro-atrial natriuretic factor (56-92) and kaliuretic peptide it is present in higher concentration in individuals with congestive heart failure. It causes the maximal increase in prostaglandin E2 (PGE2) levels of the three peptides. The known increase in PGE2 in chronic heart failure may be in part secondary to these peptides.